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Alimentiv | Protocol RP1706 (VERDICT) - Currently Recruiting

Molecule: Vedolizumab (Anti-Il23)


Study Title:

In actiVE ulcerative colitis, a RanDomIzed Controlled Trial for determination of the optimal treatment target.

AstraZeneca | Protocol D5272C00001 (EXPEDITION LEAD-IN) - Currently recruiting

Molecule: Brazikumab (Anti-IL23)


Study Title:

A 54-Week, Randomized, Double-blind, Placebo-Controlled, Parallel-group Phase 2, Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis.

Sanofi | Protocol ACT17746 (LIBERTY-UC SUCCEED) - Currently recruitring

Molecule: Dupilumab (Anti-Il4&13)


Study Title:

A Phase 2, multi-center, randomized, double-blind, placebo-controlled parallel-group study to evaluate the efficacy and safety of dupilumab therapy in patients with moderately to severely active ulcerative colitis with an eosinophilic phenotype.

Abbvie | Protocol M16-067 - Close to recruitment

Molecule: Risakizumab-anti-IL23-IV Induction


Study Title:
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Subjects with Moderately to Severely Active Ulcerative Colitis Who Have Failed Prior Biologic Therapy.

 

Eli Lily | Protocol I6T-MC-AMAP - Close to recruitment

Long Term extension study for I6T-MC-AMBG and I6T-MC-AMAC


Study Title:
A Phase 3, Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Efficacy and Safety of mirikizumab in Patients with Moderately to Severely Active Ulcerative Colitis.

 

Janssen | Protocol 78934804UCO2001 (DUET-UC) - Pending approbation

Molecule: Combination Therapy with Guselkumab (Anti-Il23 p19) and Golimumab (Anti-TNF)


Study Title:

A Phase 2b Randomized, Double-blind, Active- and Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Induction and Maintenance Combination Therapy with Guselkumab and Golimumab in Participants with Moderately to Severely Active Ulcerative Colitis.

JAMP | Protocol JAMP-AVT02-001 (EASE-PAIN Trial) - Pending approbation

Molecule: Simlandi (Adalimumab Biosimilar)


Study Title:

THE EVALUATION OF INJECTION SITE PAIN AND ADHERENCE IN PATIENTS SWITCHING FROM A LOW TO HIGH CONCENTRATION ADALIMUMAB (AVT-02) ACROSS MULTIPLE INDICATIONS.

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