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MUHC Activities

Care of the Patient With IBD Requiring Hospitalisation During the COVID-19 Pandemic.
Allez M, Fleshner P, Gearry R, Lakatos PL, Rubin DT. J Crohns Colitis. 2020 Oct 21;14(Supplement_3):S774-S779. doi: 10.1093/ecco-jcc/jjaa150. PMID: 32722757 Free PMC article.

Subjective expectations regarding longevity and future health: a cross-sectional survey among patients with Crohn’s disease.
Péntek M, Gulácsi L, Herszényi L, Banai J, Palatka K, Lakatos PL, Brodszky V, Rencz F. Colorectal Dis. 2020 Sep 13. doi: 10.1111/codi.15357. Online ahead of print. PMID: 32920967

The use of 5-aminosalicylate for patients with Crohn’s disease in a prospective European inception cohort with 5 years follow-up – an Epi-IBD study.
Burisch J, Bergemalm D, Halfvarson J, Domislovic V, Krznaric Z, Goldis A, Dahlerup JF, Oksanen P, Collin P, de Castro L, Hernandez V, Turcan S, Belousova E, D’Incà R, Sartini A, Valpiani D, Giannotta M, Misra R, Arebi N, Duricova D, Bortlik M, Gatt K, Ellul P, Pedersen N, Kjeldsen J, Andersen KW, Andersen V, Katsanos KH, Christodoulou DK, Sebastian S, Barros L, Magro F, Midjord JM, Nielsen KR, Salupere R, Kievit HA, Kiudelis G, Kupčinskas J, Fumery M, Gower-Rousseau C, Kaimakliotis IP, Schwartz D, Odes S, Lakatos L, Lakatos PL, Langholz E, Munkholm P; Epi-IBD group. United European Gastroenterol J. 2020 Oct;8(8):949-960. doi: 10.1177/2050640620945949. Epub 2020 Jul 26. PMID: 32715989

No Change in Surgical and Hospitalization Trends Despite Higher Exposure to Anti-Tumor Necrosis Factor in Inflammatory Bowel Disease in the Québec Provincial Database From 1996 to 2015.
Verdon C, Reinglas J, Coulombe J, Gonczi L, Bessissow T, Afif W, Vutcovici M, Wild G, Seidman EG, Bitton A, Brassard P, Lakatos PL. Inflamm Bowel Dis. 2020 Jul 17:izaa166. doi: 10.1093/ibd/izaa166. Online ahead of print. PMID: 32676662

Novel Negative Pressure Box for Aerosol Protection During Upper Endoscopy: A Brief Report on Safety and Barrier Performance.
Benmassaoud A, Barkun A, Gonzalez AV, Beaudoin S, Bessissow A, Bitton A, Martel M, White S, Chen YI. Am J Gastroenterol. 2020 Sep 18. doi: 10.14309/ajg.0000000000000840. Online ahead of print.

Correction to: The Future of Biosimilars: Maximizing Benefits Across Immune-Mediated Inflammatory Diseases.
Kim H, Alten R, Avedano L, Dignass A, Gomollón F, Greveson K, Halfvarson J, Irving PM, Jahnsen J, Lakatos PL, Lee J, Makri S, Parker B, Peyrin-Biroulet L, Schreiber S, Simoens S, Westhovens R, Danese S, Jeong JH. Drugs. 2020 Jul;80(10):1039-1040. doi: 10.1007/s40265-020-01333-9. PMID: 32488813 Free PMC article.

Comparative Efficacy Trials in Inflammatory Bowel Disease.
Khanna R, Zhou GY, Afif W. Gastroenterology. 2020 Sep;159(3):1182-1184. doi: 10.1053/j.gastro.2020.07.009. Epub 2020 Jul 15.

Poor Drug Sustainability in Inflammatory Bowel Disease Patients in Clinical Remission on Thiopurine Monotherapy.
Balram B, Lubov J, Theoret Y, Afif W, Bitton A, Wild G, Lakatos PL, Bessissow T. Dig Dis Sci. 2020 Jun 26. doi: 10.1007/s10620-020-06427-8. Online ahead of print. PMID: 32591969

Adenocarcinoma Within Carpet-Like Pseudopolyposis.
Xiao Y, Lakatos PL, Bessissow T. ACG Case Rep J. 2020 Jun 23;7(6):e00415. doi: 10.14309/crj.0000000000000415. eCollection 2020 Jun. PMID: 33062788 Free PMC article.

Epidemiology, mortality and prevalence of colorectal cancer in ulcerative colitis patients between 2010-2016 in Hungary – a population-based study.
Kunovszki P, Milassin Á, Gimesi-Országh J, Takács P, Szántó K, Bálint A, Farkas K, Borsi A, Lakatos PL, Szamosi T, Molnár T. PLoS One. 2020 May 14;15(5):e0233238. doi: 10.1371/journal.pone.0233238. eCollection 2020. PMID: 32407408 Free PMC article.

Aortic Stiffening Is an Extraintestinal Manifestation of Inflammatory Bowel Disease: Review of the Literature and Expert Panel Statement.
Zanoli L, Mikhailidis DP, Bruno RM, Abreu MT, Danese S, Eliakim R, Gionchetti P, Katsanos KH, Kirchgesner J, Koutroubakis IE, Kucharzik T, Lakatos PL, Nguyen GC, Papa A, Vavricka SR, Wilkinson IB, Boutouyrie P. Angiology. 2020 Sep;71(8):689-697. doi: 10.1177/0003319720918509. Epub 2020 Apr 15. PMID: 32292048 Review.

Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting.
Rubin DT, Abreu MT, Rai V, Siegel CA; International Organization for the Study of Inflammatory Bowel Disease (Lakatos PL). Gastroenterology. 2020 Jul;159(1):6-13.e6. doi: 10.1053/j.gastro.2020.04.002. Epub 2020 Apr 6. PMID: 32272113 Free PMC article. No abstract available.

Pharmacokinetics of Tumor Necrosis Factor Antagonists.
Khanna R, McCurdy J, Afif W. Gastroenterology. 2020 Jul;159(1):391-393. doi: 10.1053/j.gastro.2020.05.040. Epub 2020 May 17.

Effectiveness of ustekinumab dose escalation in Crohn’s disease patients with insufficient response to standard-dose subcutaneous maintenance therapy.
Kopylov U, Hanzel J, Liefferinckx C, De Marco D, Imperatore N, Plevris N, Baston-Rey I, Harris RJ, Truyens M, Domislovic V, Vavricka S, Biemans V, Myers S, Sebastian S, Ben-Horin S, González Lama Y, Gilletta C, Ariella BS, Zelinkova Z, Weisshof R, Storan D, Zittan E, Farkas K, Molnar T, Franchimont D, Cremer A, Afif W, Castiglione F, Lees C, Barreiro-de Acosta M, Lobaton T, Doherty G, Krznaric Z, Pierik M, Hoentjen F, Drobne D. Aliment Pharmacol Ther. 2020 Jul;52(1):135-142. doi: 10.1111/apt.15784. Epub 2020 May 15.

Concordance between tuberculin skin test and interferon-gamma release assay for latent tuberculosis screening in inflammatory bowel disease.
Alrajhi S, Germain P, Martel M, Lakatos P, Bessissow T, Al-Taweel T, Afif W. Intest Res. 2020 Jul;18(3):306-314. doi: 10.5217/ir.2019.00116. Epub 2020 Mar 20.

A further “stri(v)de” in IBD management.
Annese V, Lakatos PL. Dig Liver Dis. 2020 Jul;52(7):721-722. doi: 10.1016/j.dld.2020.02.005. Epub 2020 Mar 18. PMID: 32197889 No abstract available.

Esophageal Squamous Cell Carcinoma With Colonic Metastases.
Wiseman D, Ferri L, Lakatos PL, Fiset PO, Bessissow T. ACG Case Rep J. 2020 Feb 24;7(2):e00335. doi: 10.14309/crj.0000000000000335. eCollection 2020 Feb. PMID: 32309520 Free PMC article.

Benefits of implementing a rapid access clinic in a high-volume inflammatory bowel disease center: Access, resource utilization and outcomes.
Nene S, Gonczi L, Kurti Z, Morin I, Chavez K, Verdon C, Reinglas J, Kohen R, Bessissow T, Afif W, Wild G, Seidman E, Bitton A, Lakatos PL. World J Gastroenterol. 2020 Feb 21;26(7):759-769. doi: 10.3748/wjg.v26.i7.759. PMID: 32116423 Free PMC article.

Health-care costs of inflammatory bowel disease in a pan-European, community-based, inception cohort during 5 years of follow-up: a population-based study.
Burisch J, Vardi H, Schwartz D, Friger M, Kiudelis G, Kupčinskas J, Fumery M, Gower-Rousseau C, Lakatos L, Lakatos PL, D’Incà R, Sartini A, Valpiani D, Giannotta M, Arebi N, Duricova D, Bortlik M, Chetcuti Zammit S, Ellul P, Pedersen N, Kjeldsen J, Midjord JMM, Nielsen KR, Winther Andersen K, Andersen V, Katsanos KH, Christodoulou DK, Domislovic V, Krznaric Z, Sebastian S, Oksanen P, Collin P, Barros L, Magro F, Salupere R, Kievit HAL, Goldis A, Kaimakliotis IP, Dahlerup JF, Eriksson C, Halfvarson J, Fernandez A, Hernandez V, Turcan S, Belousova E, Langholz E, Munkholm P, Odes S; Epi-IBD group. Lancet Gastroenterol Hepatol. 2020 May;5(5):454-464. doi: 10.1016/S2468-1253(20)30012-1. Epub 2020 Feb 13. PMID: 32061322

The Future of Biosimilars: Maximizing Benefits Across Immune-Mediated Inflammatory Diseases.
Kim H, Alten R, Avedano L, Dignass A, Gomollón F, Greveson K, Halfvarson J, Irving PM, Jahnsen J, Lakatos PL, Lee J, Makri S, Parker B, Peyrin-Biroulet L, Schreiber S, Simoens S, Westhovens R, Danese S, Jeong JH. Drugs. 2020 Feb;80(2):99-113. doi: 10.1007/s40265-020-01256-5. PMID: 32002851 Free PMC article. Review.

Epidemiological data and utilization patterns of anti-TNF alpha therapy in the Hungarian ulcerative colitis population between 2012-2016.
Kunovszki P, Judit Szántó K, Gimesi-Országh J, Takács P, Borsi A, Bálint A, Farkas K, Milassin Á, Lakatos PL, Szamosi T, Molnár T. Expert Opin Biol Ther. 2020 Apr;20(4):443-449. doi: 10.1080/14712598.2020.1718097. Epub 2020 Jan 28. PMID: 31976772

Plasma Levels of C-Type Lectin REG3α and Gut Damage in People With Human Immunodeficiency Virus.
Isnard S, Ramendra R, Dupuy FP, Lin J, Fombuena B, Kokinov N, Kema I, Jenabian MA, Lebouché B, Costiniuk CT, Ancuta P, Bernard NF, Silverman MS, Lakatos PL, Durand M, Tremblay C, Routy JP; Montreal Primary HIV Infection Study, the Canadian Cohort of HIV+ Slow Progressors, and the Canadian HIV and Aging Cohort Groups. J Infect Dis. 2020 Jan 1;221(1):110-121. doi: 10.1093/infdis/jiz423. PMID: 31504638

Faecal Calprotectin Predicts Endoscopic and Histological Activity in Clinically Quiescent Ulcerative Colitis.
Hart L, Chavannes M, Kherad O, Maedler C, Mourad N, Marcus V, Afif W, Bitton A, Lakatos PL, Brassard P, Bessissow T. J Crohns Colitis. 2020 Jan 1;14(1):46-52. doi: 10.1093/ecco-jcc/jjz107. PMID: 31314884

A User’s Guide to De-escalating Immunomodulator and Biologic Therapy in Inflammatory Bowel Disease.
Hirten RP, Lakatos PL, Halfvarson J, Colombel JF. Clin Gastroenterol Hepatol. 2020 May;18(6):1336-1345. doi: 10.1016/j.cgh.2019.12.019. Epub 2019 Dec 27. PMID: 31887444 Review.

Management of Acute Severe Colitis in the Era of Biologicals and Small Molecules.
Verdon C, Bessissow T, Lakatos PL. J Clin Med. 2019 Dec 8;8(12):2169. doi: 10.3390/jcm8122169. PMID: 31817972 Free PMC article. Review.

Low Rate of Drug Discontinuation, Frequent Need for Dose Adjustment, and No Association with Development of New Arthralgia in Patients Treated with Vedolizumab: Results from a Tertiary Referral IBD Center.
Reinglas J, Gonczi L, Verdon C, Bessissow T, Afif W, Wild G, Seidman E, Bitton A, Lakatos PL. Dig Dis Sci. 2020 Jul;65(7):2046-2053. doi: 10.1007/s10620-019-05982-z. Epub 2019 Dec 7. PMID: 31813132

Disease monitoring strategies in inflammatory bowel diseases: What do we mean by “tight control”?
Gonczi L, Bessissow T, Lakatos PL. World J Gastroenterol. 2019 Nov 7;25(41):6172-6189. doi: 10.3748/wjg.v25.i41.6172. PMID: 31749591 Free PMC article. Review.

Development and Validation of a Test to Monitor Endoscopic Activity in Patients With Crohn’s Disease Based on Serum Levels of Proteins.
D’Haens G, Kelly O, Battat R, Silverberg MS, Laharie D, Louis E, Savarino E, Bodini G, Yarur A, Boland BS, Afif W, Li XJ, Hale M, Ho J, Kondragunta V, Huang B, Kuy C, Okada L, Hester KD, Bray KR, Mimms L, Jain A, Singh S, Collins A, Valasek MA, Sandborn WJ, Vermeire S, Dulai PS. Gastroenterology. 2020 Feb;158(3):515-526.e10. doi: 10.1053/j.gastro.2019.10.034. Epub 2019 Nov 8.

Anti-TNF dose escalation and drug sustainability in Crohn’s disease: Data from the nationwide administrative database in Hungary.
Kósa F, Kunovszki P, Borsi A, Iliás Á, Palatka K, Szamosi T, Vincze Á, Molnár T, Lakatos PL. Dig Liver Dis. 2020 Mar;52(3):274-280. doi: 10.1016/j.dld.2019.09.020

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