Dr. Waqqas Afif
If you are interested in learning more about any of the clinical and research studies below or would like to volunteer as a research subject, please email: miirecherche.ibdresearch@muhc.mcgill.ca.
Collaboration with Dr. Greg Rosenfeld, University of British Columbia
Study Title: Pro-Active Fecal Calprotectin Monitoring to Improve Patient Outcomes in Ulcerative Colitis: A Prospective Randomized Control Trial (PROMOTE-UC)
Study Title: Pilot study to assess de-escalation of ustekinumab therapy in patients with Crohn’s disease
Study Title: Therapeutic drug monitoring guided early optimization of Adalimumab in Crohn’s disease. A randomized open-label study
Collaboration with Dr. Sasha Bernatsky, Research Institute of the McGill University Health Centre
Sponsor: Canadian Institutes of Health Research (CIHR)
Study Title: Comparative Effectiveness and Safety of Biosimilar and Legacy Drugs
Study Title: A pilot study assessing performance of point-of-care testing for infliximab, adalimumab, C-reactive protein, and fecal calprotectin in inflammatory bowel disease patients with a secondary loss of response
Dr. Matthieu Allez
Dr. Talat Bessisow
If you are interested in learning more about any of the clinical and research studies below or would like to volunteer as a research subject, please email: miirecherche.ibdresearch@muhc.mcgill.ca.
Collaboration with Dr. Sanjay Murthy, MD, MSc, FRCPC, University of Ottawa, The Ottawa Hospital – General Campus
Study Title: A Randomized Controlled Non-Inferiority Trial Comparing Neoplasia Detection During Colonoscopy Screening With and Without Non-Targeted Biopsies in Adult Colonic Inflammatory Bowel Disease
Collaboration with Dr. Saji George, Ph.D., Associate Professor, Canada Research Chair in Sustainable Nanotechnology for Food and Agriculture
Study Title: Effect of dietary nanomaterials on the development and disease progression of inflammatory bowel disease
Collaboration with Dr. Jeffrey McCurdy, Ottawa Hospital Research Institute
Study Title: Evaluating fistula outcomes after seton removal in patients with perianal Crohn’s disease: UNFASTEN-PCD
Collaboration with Dr. Christopher Ma, MD MPH, University of Calgary
Study Title: Real-World Effectiveness and Safety of Upadacitinib for Achieving Endoscopic Remission in Moderate-to-Severely Active Ulcerative Colitis Phase IV
Collaboration with Dr. Bruce Mazer
Study Title: Transdisciplinary Centre for Biological Therapies Biobank and Registry
Sponsor: Canadian IBD Research Consortium (CIRC)
Study Title: Bowel preparation for colonoscopy among individuals with IBD: A randomized controlled trial
Dr. Alain Bitton
If you are interested in learning more about any of the clinical and research studies below or would like to volunteer as a research subject, please email: rita.kohen@muhc.mcgill.ca.
The following 4 studies are part of NIH-NIDDK IBD Genetics Consortium (IBDGC)
- Identifying genes responsible for inflammatory bowel disease
- Mechanisms of microbiota in mucosal inflammation across the biologic demarcation of Ulcerative Colitis
- Mechanisms of intestinal inflammation following ileal resection for Crohn’s Disease
- Understanding the Genetics of Inflammatory Bowel Disease: The Diversity Study
Sponsor: Dr. John D. Rioux, Montreal Heart Institute
Funding: Génome Canada (Rioux), National Institutes of Health (Rioux) and Pfizer Canada Inc. (Rioux)
Study Title: iGenoMed – CHUM: Identification of biomarkers of response to molecularly-targeted therapies in inflammatory bowel diseases
Study Title: Inflammatory Bowel Disease Epidemiology, Future Burden and Cancer Risk in Québec and Canada
as part of an initiative by the Canadian Gastro-Intestinal Epidemiology Consortium – pending approval
Collaboration with Dr. Jose Teodoro, McGill University
Study Title: Modulation of fatty acid esters of hydroxy fatty acids (FAHFA) levels in the intestine via G0S2 inhibition
Dr. Alain Bitton & Dr. Terry Sigman
Sponsor: Dr. Kenneth Croitoru, Mount Sinai Hospital, Toronto ON with funding from Crohn’s and Colitis Canada
Study Title: A Multidisciplinary Human Study on the Genetic, Environmental and Microbial Interactions that Cause IBD (GEM Project)
Dr. Peter Lakatos
If you are interested in learning more about any of the clinical and research studies below or would like to volunteer as a research subject, please email: rita.kohen@muhc.mcgill.ca
Study Title: Quality of Care Assessment of the MUHC IBD Center: Retrospective and Prospective Assessment of Quality or Care and Outcome Parameters before and after Installation of the IBD Center – on hold
Study Title: Clinical Outcomes and Therapeutic Drug Monitoring Following Switching from Intravenous Vedolizumab to Subcutaneous Vedolizumab in Patients with Inflammatory Bowel Disease; An Observational Study
Study Title: Clinical Outcomes and Therapeutic Drug Monitoring Following New Start or Switching from Infliximab Originator to Subcutaneous Biosimilars in Patients with Inflammatory Bowel Disease: an Observational Study
Study Title: Clinical Outcomes Following Switching from Ustekinumab Originator to Biosimilars in Patients with Inflammatory Bowel Disease: an Observational Study
Collaboration with Dr. Derek Rosenzweig, McGill University
Study Title: Biofabrication of a 3D gut-on-a-chip model of human inflammatory bowel disease